Perricone had his eye on the ingredient for years but hadn’t come across an effective way to deliver it to skin cells. Recently, however, he discovered a fatty acid that does the trick. The result, Perricone MD Acyl-Glutathione cream, aims to fight fine lines, sagging, and dullness—and has a pleasantly light texture, to boot (perriconemd.com; $175).

Illustrations by Hiroshi Tanabe