Christian Bale once embodied the metrosexual physical ideal in American Psycho. Eighteen years later, in Vice, he’ll play the polar opposite: a middle-aged Dick Cheney. It’s just the latest chameleon-like transformation in the actor’s varied career—and he’s not alone. Take Tilda Swinton, for example. Her breakthrough role in 1992’s Orlando mandated that she play both genders in the same movie, and the actress’s transformations haven’t slowed down since (heck, she’ll even transform herself multiple times for the sake of a fashion photo shoot); in Suspiria, she’ll play an 80-something man in one of her roles (or, at least, we assume; the details are still shrouded in mystery). The pair may represent the extremes, but they’re far from the only Hollywood stars to have physically transformed themselves on screens for the sake of a role. Show business is notoriously tough, so who’s going to let a couple of hours each morning in the makeup chair or a couple of months (or more) of intense diet and exercise get in the way of a potentially career-changing (and award-winning) role. Here, some of the most memorably onscreen transformations from the past two decades.