It’s easy, in the face of her relentlessly self-deprecating wit and much discussed bad feelings about her neck, to forget what a serious talent Nora Ephron was, and what a pioneer. The Most of Nora Ephron, out November 4 from Alfred A. Knopf, offers a refresher. Ephron bested the Hollywood boys club (the collection contains the screenplay of When Harry Met Sally), blogged before most of us knew the word (a section is devoted to her gimlet-eyed Huffington Post missives on everything from Dick Cheney to Brangelina), and mastered every other genre at which she poised her pen: journalism, profiles, essays, fiction (her thinly veiled novel about her marriage to journalist Carl Bernstein, Heartburn, is here in full), and even recipes. “Of course you can have it all,” she told the Wellesley grads at her alma mater in her 1996 commencement address. As a writer, anyhow, Ephron most certainly did.