At just 27, Jennifer Lawrence has already slipped into a wide range of life-changing roles: Her breakout role in 2010's Winter's Bone put her on the map and landed her an Academy Award nomination, her turn as Katniss Everdeen in The Hunger Games series made her a certified star, and, of course, 2012's Silver Linings Playbook led to her taking home the Best Actress Oscar. But, as Lawrence explained on Howard Stern's radio show this week, there's still one role she didn't get that haunts her to this day.

"The one thing that really killed me, like the only time I've ever been truly devastated by losing an audition―'cause most of the time you're like, 'Ah, wasn't meant to be, move on, what can you do?'―was Tim Burton's Alice in Wonderland," she said. "That one devastated me." The role of Alice ended up going to Mia Wasikowska, who Lawrence conceded was "perfect and amazing" in the role—plus, "I couldn't have had a British accent," she admitted.

The Red Sparrow star also revealed that she missed out on playing Bella Swan in the Twilight series, a role that was played to fidgety, lip-biting perfection by Kristen Stewart. "I didn't really know what [Twilight] was," Lawrence said. "When you audition when you're, like, a run-of-the-mill actor, you know, we're all auditioning for all sorts of things, you just get like five pages and they're like, 'Act, monkey!' When it came out, I was like, 'Hot damn! Whoa!'" And while Lawrence claimed that she's not jealous that Stewart ended up landing the role, she did note that pal Emma Stone did get "one thing that I was dying for."

Though the budding activist didn't elaborate about this friendly competition with Stone, the duo spoke about having both auditioned for 2010's Easy A during The Hollywood Reporter's Actress Roundtable last fall. "I auditioned for Easy A. I wanted it so bad," Lawrence, 27, said, prompting Stone, 29, to jokingly respond, "Well, guess what? You didn't get it. You didn't get it because you suck!"

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