Is there any room left in your face for a new filler? On Monday, the FDA approved Evolence, a porcine (yes, pig-derived) collagen filler that is said to last for twelve months, much longer than the old-school bovine collagen. "What's interesting about it is it doesn't require a skin test, which is great, and they say the porcine isn't allergic," says New York dermatologist Debra Jaliman, who says she has yet to try Evolence.

While the market has been flooded with scores of injectables in the last five years, Evolence is likely to compete against the wildly popular hyaluronic acid fillers, those that plump by adding and attracting moisture to the skin. "I think that Restylane, Perlane and Juvederm are a tough act to follow," says dermatologist Dennis Gross, founder of MD Skincare. "Lots of things can fill a line. The question is how natural will it look and how long will it last. Only time will tell."

Jaliman, for her part, is wondering about the target audience. "People always come in and they go, 'I want the newest, latest, best," she says. "I just wonder if people who are kosher want pork in their face."